The Future of Healthcare Polymerase Chain Reaction Market Is Closer Than You Think

Polymerase chain reaction (PCR) is used to amplify a specific segment of DNA through a thermal cycling protocol. Continuous technological advancement in the field of polymerase chain reaction are aimed to improve specificity, scalability and reliability in DNA amplification and thereby creating millions of amplicons of a target sequence in a short period of time. PCR is used for various applications, including the detection of pathogenic bacteria, disease diagnosis, molecular and genetic research, forensic DNA profiling, and parental testing. Rapid technological advancement in the polymerase chain reaction to deliver highly sensitive and optimized detection instrument, increasing prevalence of chronic and infectious disease, and growing research funding in gene therapy and molecular testing is projected to drive growth of the polymerase chain reaction market over the forecast period.

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Market Dynamics

The global polymerase chain reaction market is projected to witness significant growth over the forecast period, owing to its wide and increasing applications in various fields, which include diagnosis of infectious diseases, such as middle ear infections, tuberculosis, Lyme disease, in forensics, including DNA fingerprinting, paternity testing and in various other molecular research applications, such as DNA sequencing, DNA cloning, and gene expression. Polymerase chain reaction is used for diagnosis of genetic disease, allowing to detect inherited genetic change or spontaneous genetic mutation.

PCR is used in personalized medicine to help patients in selecting certain treatments, such as in cancer when patients have a genetic change that makes a patient more or less likely to respond to a certain treatment. Polymerase chain reaction is used to study the molecular characteristics in cancer patients, in order to deliver tailored cancer therapy in lung and colorectal cancer. Real-time PCR offers higher sensitivity and specificity in various range of nucleic acid amplification, which is used in wide research areas including infectious disease research, translational medicine to applied biology. Furthermore, technological advancement in the PCR reagents, assay, instruments and analysis tools, help to provide more customized results in various research areas, such as stem cell research, oncology and genetic disease research, pharmaceutical analytics, pharmacogenomics, plant science research and agriculture biotechnology. Such wide numbers of PCR applications in the different field of healthcare and medical research areas, are estimated to augment growth of the polymerase chain reaction market over the forecast period.

Key features of the study:

  • This report provides in-depth analysis of the polymerase chain reaction market and its market size (US$ Million) and Cumulative Annual Growth Rate (CAGR (%)) for the forecast period: 2017 – 2025, considering 2016 as the base year
  • It elucidates potential revenue opportunity across different segments and explains attractive investment proposition matrix for this market
  • This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategy adopted by the leading players

Increasing Prevalence of Chronic and Infectious Disease are Driving Growth of Polymerase Chain Reaction Market

Polymerase chain reaction is increasingly used in clinical diagnosis of infectious disease, nucleic acid amplification, paternity testing, DNA fingerprinting, detection and diagnosis of infectious disease, quality control, and personalized medicine. For instance, according to the Centers for Disease Control and Prevention (CDC), around 5,251 deaths due to the influenza infection were registered in 2015, in U.S. According to the World Health Organization (WHO), in 2015, around 32,000 estimated deaths were reported from tuberculosis and around 3, 23,000 new cases of TB cases were registered in the European region. According to the National Ambulatory Medical Care Survey: 2015 data findings, 16.8 million visits to physician offices for infectious and parasitic diseases were registered in the U.S.

Key players operating in polymerase chain reaction market include F. Hoffmann-La Roche Ltd, Bio-Rad Laboratories, Inc., Thermo Fisher Scientific Inc., Agilent Technologies, Inc., bioMérieux, S.A., Enzo Life Science, Inc., Abbott Laboratories, Takara Bio Inc., Becton, Dickinson and Company, and Danaher Corporation.

Polymerase Chain Reaction Market Pipeline Insight and Therapeutic Assessment Reviewed by 2018-2026

The Global Polymerase Chain Reaction Market, by Product Type (Instrument (Real Time PCR, Digital PCR, and Others) Reagents and Consumables)), by End User (Clinical Diagnostics, Academic and Research Laboratories, Forensic Laboratories, and Others), was valued US$ 3.7 billion in 2017 and is projected to exhibit a CAGR of 8.8%over the forecast period (2018 – 2026) as highlighted in a new report published by Coherent Market Insights.

Polymerase chain reaction (PCR) is laboratory technique used to amplify a single copy or a few copies of DNA segment to make several thousand to millions of copies of a particular DNA sequence. PCR has extensive applications in various fields, which includes diagnosis of infectious diseases, such as middle ear infections, tuberculosis, Lyme disease, DNA fingerprinting, paternity testing and in various other molecular research applications, such as DNA sequencing, DNA cloning, and gene expression.

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Moreover, increasing prevalence and incidence of infectious and chronic disease coupled with increasing need to develop advanced polymerase chain reaction system to deliver rapid and inexpensive quantitative detection of target sample, are the major factors driving growth of global polymerase chain reaction market over the forecast period. Digital PCR (dPCR) is a new approach to nucleic acid detection and quantification. Digital PCR provides ultrasensitive and absolute nucleic acid quantification. dPCR is particularly used in rare allele detection and for absolute quantification of gene expression and viral load. Moreover, advancement in the dPCR leads to the introduction of droplet digital PCR (ddPCR). ddPCR is method of performing digital PCR, using water-oil emulsion droplet technology. In ddPCR technology sample is fractionated into 20,000 droplets, and PCR amplification of the template molecules occurs in each individual droplet, then by counting the positive droplets provides precise and absolute target quantification. ddPCR technology uses reagents and workflows, similar to those used for most standard probe-based assays.

Continuous research and development and technology advancements in polymerase chain reaction system allows to introduce the better and affordable instruments, reagent and consumables in the field of clinical diagnosis. For instance, in March 2018, Sekisui Diagnostics launched Silaris Influenza A&B Test: an affordable, polymerase chain reaction (PCR) testing platform designed specifically for point-of-care (POC) infectious disease diagnosis. In October 2017, Diatech Pharmacogenetics srl launched easyPGX: a ready to use in-vitro diagnostic real-time PCR product line and Helix: a polymerase chain reaction kit for the extraction of circulating free DNA from plasma.

Moreover, in September 2015, Bio-Rad Laboratories launched droplet digital PCR (ddPCR) Supermix for Residual DNA Quantification. The new supermix designed to use with Bio-Rad’s Droplet Digital PCR Systems, and allows highly precise and sensitive method for DNA measurement. In November 2014, Chai Biotechnologies Inc. introduced Open qPCR: Real-Time PCR Thermocycler. The new instrument is designed to for genetic genotyping, pathogen detection, and relative DNA quantification. Moreover, In April 2014, Bio-Rad Laboratories launched Precision Blue Real-Time PCR Dye. The new Precision Blue dye is compatible with Bio-Rad’s universal qPCR supermixes, and can be used with all Bio-Rad’s CFx real time PCR systems. In November 2012, Life Technologies Corporation launched its Applied Biosystems QuantStudio Dx Real-Time PCR Instrument, in Europe. The new PCR instrument is designed to be used in the clinical diagnostic laboratory tests such as pathogen detection, gene expression analysis, SNP genotyping, mutation detection, micro-RNA and other non-coding RNA analysis.

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Some of the major players involved in global polymerase chain reaction market include F. Hoffmann-La Roche Ltd, Bio-Rad Laboratories, Inc., Thermo Fisher Scientific Inc., Agilent Technologies, Inc., bioMérieux, S.A., Enzo Life Science, Inc., Abbott Laboratories, Takara Bio Inc., Becton, Dickinson and Company, and Danaher Corporation.

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Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.