Amebiasis Treatment Market Growth Analysis, Share, Demand by Regions, Types and Analysis of Key Players- Research Forecasts to 2026

Increasing approvals and launches of new drugs indicated for the treatment of amebiasis is expected to be a major factor for growth of amebiasis treatment market. For instance, in 2017, Dr. Reddy’s Laboratories received U.S. Food and Drug Administration (FDA) approval for its Minolira (minocycline) extended-release tablets, indicated for the treatment of a variety of bacterial infections and as adjunctive therapy in acute intestinal amebiasis. Moreover, in 2016, Rising Pharmaceuticals, Inc.—a subsidiary of Aceto Corporation—launched  Metronidazole Tablets, 250mg and 500mg, generic version of Flagyl manufactured by G.D. Searle, LLC’s, indicated for the treatment of amebiasis and a variety of anaerobic bacterial infections. Click To Read More On Amebiasis Treatment Market

In 2016, Mylan Pharmaceuticals Inc. received ANDA approval for its Doryx (Doxycycline Hyclate) Delayed-Release Tablets, 50 mg, indicated for the treatment of acute intestinal amebiasis. Furthermore, increasing prevalence of amebiasis in region with poor sanitation facilities such as Africa and some countries in Asia Pacific is expected to lead to increasing demand for its treatment, which in turn is expected to drive growth of the amebiasis treatment market in the near future.

Amebiasis Treatment Market Regional Analysis

Africa is expected to show a significant growth in the global amebiasis treatment market over the forecast period, owing to high prevalence rate of amebiasis due to poor sanitation and low availability of clean drinking water. For instance, according to data published by United Nations Department of Economic and Social Affairs (UNDESA), in 2014, around 115 people in Africa die every hour from diseases linked to poor sanitation, poor hygiene, and contaminated water.

In Sub-Saharan Africa around 40% of the 783 million people do not have access to a clean source of drinking water. Furthermore, Asia Pacific region is expected to show significant growth in amebiasis treatment market over the forecast period, owing to increasing prevalence of amebiasis in some rural areas of India and China. For instance, according to data published on National Health Portal of India, in 2015, amebiasis affected about 15% of the total population in India.

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Amebiasis Treatment Market Key Players

Key players operating in amebiasis treatment market include Pfizer Inc., Impax Laboratories, Lupin Pharmaceuticals, Inc., Sanofi, Actelion Pharmaceuticals Ltd., Glenmark Pharmaceuticals, Sun Pharmaceutical Industries Inc., Heritage Pharmaceuticals Inc., Mission Pharmacal Co., Novel Laboratories, and others.

Key players in the market are focusing on launching generic versions of branded medicines indicated for treatment of amebiasis. For instance, in 2017, Mayne Pharma Group Limited received FDA approval for its Doxycyline Hyclate IR Tablets, first generic to Acticlate. Doxycycline Hyclate 75 mg and 150 mg are tetracycline class drugs indicated for adjunctive therapy for acute intestinal amebiasis.

Hypertrophic Cardiomyopathy (HCM) Therapeutics Market 2026 Emergence By Key Opinion Leaders, Current Industry Scenario, Future Merchandise Size, Macro Economical And Governing Factors

Hypertrophic Cardiomyopathy (HCM) is a genetic condition of heart muscle associated with the thickened heart muscle wall. HCM is caused due to the changes or mutation in one or more genes, which is inherited. Hypertrophic cardiomyopathy affects the muscular wall of heart making them stiff. This thickening makes harder for the heart to pump blood out of the heart and around the body. Shortness of breath, palpitations, chest pain, and fainting & light headaches are some of the major symptoms of hypertrophic cardiomyopathy. In some people, a number of other associated conditions may develop as a result of HCM, which includes abnormal heart rhythms or arrhythmias, including heart block, and endocarditis.

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Hypertrophic Cardiomyopathy (HCM) Therapeutics Market Drivers

Demand for Hypertrophic Cardiomyopathy (HCM) therapeutics is expected to grow over the forecast period, owing to increasing prevalence of hypertrophic cardiomyopathy worldwide. For instance, according to the American Heart Association (AHA): March 2016, hypertrophic cardiomyopathy affects around 500,000 people in the U.S annually. Furthermore, according to the European Heart Journal, July 2014 findings, HCM occurs in 1:500 people in the general population worldwide, which reported around 700,000 affected Americans. Also, around 2 million people in India and China are affected with hypertrophic cardiomyopathy.

Growing number of research studies in the field of hypertrophic cardiomyopathy treatment by private and government organizations lead to develop an efficient treatment option such as calcium channel blockers and antiarrhythmic agent, enabling significant traction in these market. For instance, in May 2018, MyoKardia, Inc. initiated the PIONEER open-label extension (OLE) study of its investigational drug: mavacamten, to be used in symptomatic, obstructive hypertrophic cardiomyopathy. Furthermore, a study published in Journal of General Physiology in May 2018, stated that, researchers from Washington State University discovered link between genetic mutation to hypertrophic cardiomyopathy (HCM) and mode of disrupting the heart’s normal function.

Hypertrophic Cardiomyopathy (HCM) Therapeutics Market Competitive Landscape

Key players operating in the Hypertrophic Cardiomyopathy (HCM) therapeutics market include Sanofi S.A., Merck & Co., Pfizer, Inc., Mylan N. V., MyoKardia, Inc., Teva Pharmaceutical Industries Ltd., and Novartis AG.

Key players in the market are focusing on organic growth strategies such as collaborations and regulatory product approval in order to gain maximum market share and retain leading position in the market. For instance, in September 2014, Sanofi S.A. and MyoKardia, Inc. collaborated to discover and develop targeted therapeutics for genetic heart diseases such as Hypertrophic Cardiomyopathy, Cardiomyopathy and Dilated Cardiomyopathy (DCM). In May 2016, U.S. Food and Drug Administration (FDA) granted MyoKardia’s novel drug: MYK-461; as an orphan drug designation for treatment of symptomatic obstructive hypertrophic cardiomyopathy. The drug MYK-461 is the first therapy developed to treat hypertrophic cardiomyopathy.

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Hypertrophic Cardiomyopathy (HCM) Therapeutics Market – Regional Analysis

On the basis of region, Hypertrophic Cardiomyopathy (HCM) therapeutics market is segmented into North America, Latin America, Europe, Middle East, Asia Pacific, and Africa. North America is projected to drive growth of the Hypertrophic Cardiomyopathy (HCM) therapeutics market, owing to increasing prevalence of obesity among the younger population in North America and increasing preference towards a sedentary lifestyle, which are the primary factors augmenting demand for hypertrophic cardiomyopathy therapeutics in these region.

Aspergillosis Treatment Market Trends and Forecast to 2026- Industry Analysis by Geographical Regions, Type and Application

Aspergillosis is a group of diseases that occur from aspergillus infection. Aspergillus is a fungus whose spores are present in the air, but does not normally cause illness. Individuals with damaged lungs, sensitive immune system, and allergies are more prone to Aspergillus induced infection. Common Aspergillus infections include invasive Aspergillosis, non-invasive Allergic Pulmonary Aspergillosis (ABPA), and Chronic Pulmonary and Aspergilloma (CPA). Invasive aspergillosis is uncommon and occurs primarily in immunocompromised people. Chronic pulmonary aspergillosis is rare pulmonary disease, which increases symptoms of respiratory disorders such as asthma. click To Read More On Aspergillosis Treatment Market

Aspergillosis Treatment Market Dynamics

Increasing prevalence of Aspergillosis and favorable government regulations are the major factors driving growth of the Aspergillosis treatment market. According to a study published in Journal of Fungi 2016, CPA is estimated to affect nearly three million people globally making it major health problem resulting in mortality and morbidity. Aspergillosis infection can be treated with antifungal and corticosteroids drugs. Corticosteroid drugs are prescribed for allergic bronchopulmonary aspergillosis treatment. These drugs reduce inflammation and lowers respiratory symptoms such as coughing and wheezing. Some of the most frequently used drugs are methylprednisolone, prednisolone and prednisone. The U.S. Food & Drug Administration (FDA) approved various drugs for Aspergillosis infection treatment.

Aspergillosis Treatment Market Competitive Analysis

Major players operating in the aspergillosis treatment market include Abbott laboratories, AstraZeneca plc, Eli Lilly and Company, GlaxoSmithKline, Johnson & Johnson Services, Inc., Mylan Pharmaceuticals, Inc., Novartis AG, Pfizer, Inc., and Takeda Pharmaceutical Company Ltd.

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Aspergillosis Treatment Market Regional Insights

Regional segmentation of Aspergillosis treatment market by Coherent Market Insights, includes North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America Aspergillosis treatment market is expected to hold a dominant position, due to increasing government initiatives for diagnosing and treatment of infection. In 2016, the Infectious Diseases Society of America (IDSA) published new guidelines for the diagnosis and treatment of infections due to Aspergillus species.

The document offers guidance on non-culture-based identification of Aspergillus infections and dejects the use of combination anti-fungal therapy for primary management. The guidelines also define therapy of isavuconazole, a new U.S. FDA approved anti-fungal drug in March 2015 to treat mucormycosis and aspergillosis. Asia pacific Aspergillosis treatment market share is expected to witness significant growth during the forecast period, owing to large volume of untreated patients.

Clostridium Difficile Infection Treatment Market Trends Forecast Analysis by Manufacturers, Regions, Type and Application to 2026

Clostridium difficile, which produces gram-positive bacterium, is an anaerobic toxin that gets transmitted through fecal-oral route. Clostridium difficile infection occurs during antibiotic treatment or can be caused due to healthcare associated infection with clinical manifestation ranging from asymptomatic infection to watery diarrhea or serious intestinal condition such as colitis and colonic perforation. This infection can be diagnosed by enzyme immunoassays for toxins or Clostridium difficile glutamate dehydrogenase (GDH) and nucleic acid amplification tests for Clostridium difficile toxin genes or endoscopy.

Limited types of drugs such as metronidazole, fidoxamycin and vancomycin are only available for the treatment of Clostridium difficile infection. In case of any severe pain or toxic megacolon in abdominal wall, patients undergo surgery for removal of infected portion. High prevalence of this disease and occasional disease outbreaks in the emerging economies are expected to drive growth of Clostridium Difficile Infection Treatment Market.

The Global Clostridium Difficile Infection Treatment Market – Regional Analysis

On the basis of region, the global Clostridium difficile infection treatment market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to be a dominant market region over the forecast period due to increasing prevalence of Clostridium difficile infection in this region. Furthermore, European economies are expected to face a decline in Clostridium difficile infection treatment market due to mandatory surveillance, monitoring of antibiotic prescriptions, and reformed compliance with isolation, hand washing, and hygiene protocols. The statistics revealed by Public Health England suggests that Clostridium difficile infection has substantially decreased from 55,498 cases to 13,361 cases between the period of 2007- 2008 and 2013 -2014. Asia pacific is the largest market region due to poor healthcare infrastructure and facilities, and lack of hygiene conditions.

The Global Clostridium Difficile Infection Treatment Market – Competitors

The major players operating in the Clostridium difficile infection treatment market include Merck & Co., Inc., Baxter International Inc., Sanofi S.A., Pfizer limited, Novartis, Astellas Pharma Inc., Eli Lilly and Company, AstraZeneca Plc., Actelion Pharmaceuticals Ltd (Sub. of Johnson & Johnson Services, Inc.), and Mylan N.V.

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Furthermore, development of better diagnostic tools will also drive growth of Clostridium difficile infection treatment market. For instance, Quidel introduced Solana, a FDA approved molecular assay for qualitative Clostridium difficile infection detection. The company claims it as a quick and accurate diagnosis that can process 12 samples in one-shot in 35 min. Moreover, in 2017, Roche developed a Cobas Cdiff nucleic acid test for use on an automated Cobas Liat System, which uses a real time PCR for the detection of Clostridium difficile toxin B. Therefore, therapeutic and diagnostic advancements will enhance Clostridium difficile infection treatment market.

Hemostasis & Tissue Sealing Agents Market With With Top 20 Countries data : Research Analysis including Growth Factors, Types and Application to 2026

The Global Hemostasis & Tissue Sealing Agents Market was valued at US$ 3,236.2 million in 2017 and is expected to witness a robust CAGR of 8.1% over the forecast period (2017–2025).

Hemostats and tissue sealants are used in a wide range of medical applications that include hernia fixation surgery, orthopedic surgery, spinal injury, trauma or accident wound closure, ophthalmic injuries or replacements, burns, neurosurgeries, urological disorders, and other chronic conditions to control excessive bleeding. Thus, increasing number of surgical procedures is expected to be a major factor augmenting growth of the global hemostasis and tissue sealing agents market.

For instance, according to the Wound Management Innovation Center, 2015, wounds are estimated to affect over 433,000 people in Australia and the economic burden is estimated to be around US$ 2.85 billion per year. Moreover, according to The World Bank in 2012, the number of surgical procedures performed per 100,000 population were accounted to be 4,511 globally.

Key players operating the global hemostasis & tissue sealing agents market include Cryolife, Inc. Baxter International, Inc., Ethicon LLC, Integra Lifesciences Corporation, Becton, Dickinson & Company, Cohera Medical, Inc., Pfizer, Inc., Medtronic plc, B. Braun Melsungen AG, MIL Laboratories Pvt. Ltd, Advanced Medical Solutions Group Plc, and others.

Market players are launching innovative products to sustain their position in the global hemostasis & tissue sealing agents market

Key players in the market are focused on expansion of their presence through launch of new product lines in emerging economies. For instance, in March 2018, Baxter International, Inc. completed acquisition of two hemostat products from Mallinckrodt Plc and announced to widen its customer base through launch of RECOTHORM and PREVELEAK hemostat sealant in Japan.

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Moreover, players are also focusing on offering innovative products, in order to enhance their market share. For instance, in January 2018, Ethicon LLC, a part of Johnson & Johnson Medical Devices Companies, introduced SURGICEL powdered absorbable hemostat that assists to combat disruptive bleeding on broad and oozing surfaces.

Dravet Syndrome Treatment Market 2018 Opportunities, Competition from Opponents, Dynamics, Demand, Challenge and Risk and Forecast to 2026

Dravet Syndrome Treatment Market Drivers

Increasing research & development activities for the development of novel drugs for Dravet syndrome, and subsequently their approval in key regions such as North America and Europe is expected to fuel growth of the global Dravet syndrome treatment market in near future. In 2017, Epygenix Therapeutics, Inc.—a biopharmaceutical company—received U.S. Food and Drug Administration (FDA) orphan drug designation for its EPX-300, indicated for the treatment of Dravet syndrome. In 2017, Ovid Therapeutics—a U.S.-based biopharmaceutical company—received orphan drug designation for TAK-935/OV935 by U.S. Food and Drug Administration (FDA).

In February 2018, Zogenix Inc. announced FDA approval of breakthrough therapy designation to ZX-008, its Phase III drug for seizures associated with Dravet Syndrome. In 2017, OPKO Pharmaceuticals LLC, a subsidiary of OPKO Health, Inc., received orphan drug designation from U.S. FDA for its oligonucleotide-based AntagoNAT (CUR-1916) indicated for the treatment of Dravet Syndrome, and the company also received orphan drug designation for its CUR-1916 from European Commission during the same year. Furthermore, strategic collaborations among key players in market for the development and manufacturing of drugs indicated for treatment of Dravet syndrome is also expected to drive growth of the Dravet syndrome treatment market.

Dravet Syndrome Treatment Market Key Players

Key players operating in the Dravet syndrome treatment market include Epygenix Therapeutics, Inc., Ovid Therapeutics, GW Pharmaceuticals Plc., Takeda Pharmaceutical Company Ltd, Zogenix, Inc, OPKO Health Inc., Biocodex S.A., Biscayne Neurotherapeutics, Inc., and PTC Therapeutics, Inc. Key players in the market are focusing on receiving approval for their novel drugs, from major regulatory bodies such as FDA and European Commission. For instance, in 2017, Biscayne Neurotherapeutics, Inc., received an Orphan Drug designation from the U.S. FDA for its compound BIS-001 indicated for the treatment of Dravet syndrome.

Dravet Syndrome Treatment Market Regional Analysis

North America is expected to a hold dominant position in the global Dravet syndrome treatment market, owing to increasing initiatives and funding by various organizations to support the development of new treatment for Dravet syndrome. For instances, in 2017, The Dravet Syndrome Foundation—a U.S.-based non-profit organization dedicated to funding the highest caliber research on Dravet syndrome—funded a total amount of US$ 3,600,000 for the development of novel treatment methods for Dravet syndrome. In 2011, Dravet Syndrome Foundation granted an undisclosed amount to U.S.-based OPKO Health, Inc., to support the company’s efforts to develop potential therapeutic agents for the treatment of Dravet syndrome.

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The market in Europe is expected to exhibit significant growth in the Dravet syndrome treatment market, owing to increasing research and development activities being adopted by key players present in the region.

Hepatitis Vaccine Market Research, Size, Share Analysis by Manufacturers, Regions, Type and Application to 2026

Hepatitis is one of the most prevalent infectious disease across the globe, it attracted attention from health bodies such as World Health Organization (WHO) due to its severity. Increasing incidence of hepatitis worldwide is estimated to drive growth of the hepatitis vaccine market.  According to World Hepatitis Report published in 2017 by WHO, an estimated 325 million people worldwide are living with chronic hepatitis B virus infection (HBV) or hepatitis C virus (HCV) infection. Click to Read More On Hepatitis Vaccine Market

Moreover, an estimated 1.34 million deaths in 2015, were caused due to viral hepatitis. Around 1.75 million people were infected with hepatitis B virus infection (HCV) in 2015. Increasing global population (live births) is another factor driving growth of the hepatitis vaccine market. As per statistics given by the World Population Report published in 2017, world population would surpass mark of 9 billion by 2025 thereby adding more live birth each year.

According to guideline published by WHO, vaccine for hepatitis B has to administer within first 24 hour of the birth in order to prevent the hepatitis B infection to infant. Furthermore, increased awareness amongst masses about benefits of hepatitis vaccination would further aid in market growth for the hepatitis vaccine market.

Regional Dynamics

On the basis of regions, hepatitis vaccine market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to dominate the hepatitis vaccine market, owing to high healthcare spending and availability of robust healthcare infrastructure in the region. According to Centre for Disease Control (CDC) data in 2016, the U.S. had 0.6 cases per 1, 00,000 population. Even though this rate of incidence is low as compared to regions such as Asia Pacific and Africa, still due to highest healthcare spending by U.S. population hepatitis vaccine North America is lucrative market for hepatitis vaccine market.

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Asia Pacific has greatest burden of hepatitis (154 million people with hepatitis B) currently as mentioned in World Hepatitis Report, 2017 and it is attractive market for hepatitis market due to the larger population getting infected from the hepatitis. According to the WHO, it is estimated that 2% to 5% of general population is affected chronically in Asia Pacific. Prevalence of hepatitis B is the highest in Middle East & Africa where adult population is chronically infected.

Competitive Analysis

Key players present in the hepatitis vaccines market are Merck and Company, GlaxoSmithKline, Sanofi Pasture, CSL Behring GmbH, Novartis AG and Pfizer Inc. Few leading brands in hepatitis vaccine market are Engerix-B, Havrix (Glaxosmithkline), Recombivax, Vaqta (Merck and Company), Euvax – Avaxim (Sanofi Pasteur), and Shanvac B (Shantha Biotech)

However cost associated with these vaccines in both Hepatitis A and Hepatitis B is matter of concern. Government support is essential for the common affordability of hepatitis vaccine, even though WHO and many national government took initiative to better target hepatitis vaccine. Accessibility of these vaccines is still low especially in remote locations in emerging markets such as Asia Pacific and Africa where increased incidence is observed, which may limit the growth of market. There is attractive opportunity to introduce hepatitis C vaccine as it is one of most prevalent type of hepatitis after hepatitis B and has no vaccine available for it.

Anaplastic Astrocytoma Treatment Market Trends Forecast Analysis by Manufacturers, Regions, Type and Application to 2026

Anaplastic Astrocytoma Treatment Market: Driver

Increasing number of drug candidate in pipeline, which may receive approval over the forecast period is expected to drive growth of the global anaplastic astrocytoma treatment market. Currently, there is only a drug, temozolomide (Temodar), approved by U.S. FDA for Anaplastic Astrocytoma. Temodar is an alkylating agent that has been approved for both conditions, newly diagnosed patients as well as refractory anaplastic astrocytoma patients, who have witnessed disease progression in spite of taking drug containing nitrosourea and procarbazine. Click To Read More On Anaplastic Astrocytoma Treatment Market

However, there are multiple products in pipeline for the treatment of anaplastic astrocytoma. For instance, DCC-2618, a drug candidate developed by Deciphera Pharmaceuticals, Inc. is currently in Phase 1 clinical trials. The drug has also been granted orphan drug designation for the treatment of anaplastic astrocytoma and glioblastoma multiforme (GBM) in September 2017.

Moreover, an experimental drug PAC-1 was cleared for the clinical trial of patients with anaplastic astrocytoma in November 2017. The drug candidate is being developed by Vanquish Oncology, Inc. The trial will determine if the drug candidate is safe to use in combination with a standard chemotherapy drug, temozolomide.

Anaplastic Astrocytoma Treatment Market: Key Players

Key players operating in anaplastic astrocytoma treatment market includes Merck & Co., Inc., Teva Pharmaceutical Industries Ltd., Mylan N.V., Pfizer, Inc., and Novartis AG. Roche AG has also product for anaplastic astrocytoma in pipeline, currently. Moreover, medium-sized generic manufacturers such as Perrigo Company Plc and Cipla Ltd. also have presence in the market.

Anaplastic Astrocytoma Treatment Market: Regional Analysis

North America is expected to account for major share in global anaplastic astrocytoma treatment market, owing to higher awareness about rare diseases such as anaplastic astrocytoma, and also, presence of leading clinical-stage companies in the region. For instance, a study sponsored by Burzynski Research Institute, headquartered at Texas, U.S., is testing antineoplaston therapy (atengenal + astugenal) in clinical trials. The study is currently in phase 2 clinical trials. Furthermore, a clinical trial sponsored by Northwell Health in collaboration with Genentech, Inc. (subsidiary of Roche AG) is testing safety and efficacy of Erlotinib for anaplastic astrocytoma. The study is currently in Phase 1/2. Approval of these pipeline products over the forecast period would boost growth of North America anaplastic astrocytoma treatment market.

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Moreover, the approval of generics for temozolomide will play a vital role in increasing adoption of drug, especially in emerging economies in regions such as Asia Pacific and Latin America. In 2016, FDA approved the Amerigen Pharmaceuticals Limited’s generic version of Temodar. The company’s main facility is in Jiangsu Province, China. Leading global generic players such as Mylan N.V. has also received approval for generic version of Temodar in July 2016. The entry of generic drugs is expected to support growth of the anaplastic astrocytoma treatment market.

Dementia Drugs Market 2026 Driving Factors, Industry Analysis, Investment Feasibility And Trends

Dementia is one of the most prevalent neurodegenerative diseases in which patients suffer from various behavioral changes, as a primary symptoms such as decline in memory or other thinking skills and can gets worse as condition progresses. It majorly affects people of aged 65 years and above. Currently, there is no curative therapy available for dementia disease. However, drugs for dementia therapy are in pipeline, which are expected to be launched in the near future, in turn propelling growth of the dementia drugs market.

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Market Dynamics

Increasing aging population along with its associated complications is the major driving factor for growth of the dementia drugs market. For instance, according to Centers of Disease Control and Prevention (CDC), 2013, five million people were suffering from AD and the number is expected to rise up to 14 million by 2050, in the U.S. Moreover, according to World Health Organization (WHO), 2017, around 47 million people suffer from dementia and around 10 million new cases are reported annually. Increasing incidence of dementia coupled with growing demand for therapy is expected to favor growth of the dementia drugs market in the near future. According to Australian Institute of Health and Welfare (AIHW) estimates, the number of people with dementia is expected to reach to around 400,000 by 2020, and around 900,000 by 2050. Moreover, the National Health and Medical Research Council (NHMRC) is working in collaboration with the Australian Research Council (ARC) to prioritize and fund new dementia research projects and translate research to improve prevention, diagnosis, treatment, and care for dementia patients.

Increasing number of pipeline products is expected to drive growth of the dementia drugs market

Major factors fueling growth of the dementia drugs market include the large number of drugs in the pipeline, which are expected to enter into the market by 2020-2022. According to the study published by Translational Research and Clinical Intervention, in September 2017, it is recorded that 105 new drugs in pipeline, out of which 25 are in phase one, 52 in phase two and 28 are in phase three. These new products use novel approaches such as immunotherapy to target amyloid beta, beta-site amyloid precursor protein cleaving enzyme 1 inhibitors, tau aggregation inhibitor, and serotonin 5-HT6 receptor antagonist. Furthermore, increasing collaborations amongst companies for developing drugs in joint efforts is also boosting growth of the market. For instance, in November 2017, Novartis and Amgen, along with the Banner Alzheimer’s Institute, announced a collaboration to assess potential of the BACE1 inhibitor CNP520 to prevent or delay symptoms of Alzheimer’s disease. However, failure of investigational candidate in late stage is expected to be a huge setback in the current Alzheimer’s drugs market. For instance, in February 2017, an external data monitoring committee warned that Merck & Co., Inc. terminated study of Alzheimer’s candidate verubecestat due to potential failure in a Phase II/III study.

Dementia Drugs Market Regional Outlook – Growing Integration of Healthcare and IT to boost demand in emerging economies

On the basis of geography, the global dementia drugs market can be segmented into six major regions: North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. North America is expected to hold the largest market, owing to major approval of drugs in this region and favorable reimbursement scenarios. Asia Pacific is expected to emerge as a major market in the near future, majorly due to the growing geriatric population and Alzheimer’s disease cases, especially in China, India. This in turn, is expected to create lucrative opportunities for growth of the market. For instance, according to Alzheimer’s Disease International Association, in 2015, East Asia is the region with the maximum number of people living with dementia (9.8 million), followed by Western Europe (7.4 million).

Some of the top companies operating in the dementia drugs market are Eisai, Inc., Janssen Pharmaceuticals, Inc., Biogen Pharmaceuticals, Forest Laboratories, Inc., Eli Lilly and Company, Novartis AG, Sanofi S.A., AstraZeneca GmbH, F. Hoffmann-La Roche, Merck & Co., Inc.., Valeant Pharmaceutical International, Pfizer Inc., and Teva Pharmaceuticals Industries Ltd.

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Sugar-based Excipients Market 2025 Distributors/Traders, Strategy Analysis, Marketing Channel With Forecasted Data

An excipient is an inactive substance formulated with the active ingredient of a medication for the purpose of bulking-up Route of Administration that contain potent active ingredients. These substances improve bulkiness and dissolution rate of the drug and are crucial in drug delivery within the body. A sugar-based excipient is required if the conventional tablet contains a bitter drug substance or, more importantly, if the tablet is chewable. Sweeteners are added in tablets to impart sweetness to the drugs. Sucrose is the standard against, which all sweeteners, both artificial and natural, are measured. Apart from being sweeter than sucrose, artificial sweeteners have the advantage of not disturbing blood sugar levels of pre-diabetic or diabetic patients, and they are considered to be non-cariogenic. Sugar-based excipients are widely used as ingredients in pharmaceutical tableting. They are used for taste masking of bitter drugs and as bulking agents. Dextrose, fructose, mannitol, sorbitol, and xylitol are few examples of sugar-based excipients that are mainly used.

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Sugar-based Excipients Market Dynamics

Increasing use of co-processed excipients and rising development of orally disintegrating tablets (ODTs) are major factors that are expected to boost growth of sugar-based excipients market over the forecast period. ODTs are solid dosage forms containing medicinal substances, which disintegrate rapidly, generally in few seconds, when placed on the tongue. Research on delivering biological molecules through the oral route have widened the scope of ODT technology, which further drive growth of the market. According to the American Pharmaceutical Review 2016, over 35 products have been launched using Zydis ODT technology in over 60 countries worldwide. Furthermore, rising use of sugar alcohols such as mannitol in a wide range of oral dosage and high adaptability in formulation technologies such as ODTs are expected to drive the sugar-based excipients market growth over the forecast period. Sugar alcohol is granular and white like sugar, and is used as a sugar alternative. The sugar alcohols differ in calorie content and sweetness level. Their sweetness level ranges from 50% to 100% that of sugar.

Demand for oral Route of Administration due to increased use of tablets, capsules, solutions, and emulsions for various therapeutic areas is anticipated to drive market growth. Oral route of administration form the largest category of pharmaceutical dosage. Although an excipient is pharmacologically inactive and does not interact with the active drug ingredients or other excipients, few excipients meet the criteria. Some sugar-based excipients can cause side effects and therefore should be avoided. For instance, Aspartame, which is used as a sweetener in drugs are not prescribed to patients with phenylketonuria.

Sugar-based Excipients Market Regional Insights

On the basis of region, the global sugar-based excipients market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America sugar-based excipients market is expected to hold a dominant position over the forecast period, owing to increased usage for generic drugs in the region. Increasing investments in drug development and rising production of generic drugs will drive growth of sugar-based excipient market in Europe. Significant growth in the healthcare and pharmaceutical industry, favorable government policies, low-cost manufacturing, and increasing demand for generic drugs, especially in emerging economies directly contributes to the market growth. According to the Food and Drug Administration (FDA) data, in 2017, Indian firms received around 40% of the new U.S. approvals for generics with a wider base of companies.

Sugar-based Excipients Market Competitive Landscape

Some of the key players operating in the global sugar-based excipients market include Ashland Inc., Associated British Foods Plc, BASF SE, Colorcon, Inc., Cargill, Inc., DFE Pharma, FMC Corporation, MEGGLE AG, Roquette Group, and The Lubrizol Corporation.