Optogenetics is the technique in which optically-activated proteins are used to control neuronal function. It is one of the recent development in neuroscience, which provides treatment options to incurable disease such as retinal diseases, Parkinson’s, and Alzheimer’s disease. Optogenetic techniques allow activation or inhibition of the specific neurons with a high degree of spatial, temporal, and neurochemical precision. In this technique, gene which code for light sensitive protein is taken out of algae species. This protein is actually act as ion channel that opens or close in response to specific wavelength of light. The gene which code for this protein is inserted into specific neuron in the brain and it express to produce this light sensitive protein. On flashing light on specific neural cell, there is conduction of the neural signal. This technique can be utilized to control movement of neuron and to understand functioning of brain cells at cellular level.
Factors responsible for growth of the optogenetics actuators & sensors market are rise in burden of retinal disease and neurological disorders, rapid development and research in the field of optogenetics, and government initiatives such as funding support for development of this field. Optogenetics allow to understand which biochemical and physiological pathway is working for cause of particular disease, which may help to find treatment for particular disease by flashing blue light on specific neural cells. According to World Health Organization’s factsheet in 2016, age-related macular degeneration (AMD) ranked third among the global causes of visual impairment with a blindness prevalence of 8.7 %. Age-related macular degeneration is the primary cause of visual deficiency in industrialized countries. Alzheimer’s disease is another potential area in which optogenetics could give sustainable treatment solution. According to World Alzheimer Report in 2016, there were an estimated 46.5 million Alzheimer’s disease patients across the world. Moreover, every three second, one new case of Alzheimer’s disease is registered, worldwide.
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On the basis of geography, optogenetics actuators & sensors market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to be the dominant region in the optogenetics actuators & sensors market. Most of the optogenetics related research is ongoing in the U.S., which is why it serves as a conducive environment for growth of the market. There is strong government funding to carry research and development in this field as optogenetics has potential to better understand pathophysiology in chronic neural disease such as Alzheimer’s disease and Parkinson’s disease, which has high prevalence rate in the U.S. National Institute of Mental Health of the National Institutes of Health (NIH) in 2016, awarded grant of US$ 1.4 million to Max Planck Florida Institute for Neuroscience and NYU Langone Medical Center for research in optogenetics. Companies such as GenSight Biologics have its optogenetics research platform GS030 in preclinical stage.
Key players present in the optogenetics actuators & sensors market are Bruker, Circuit Therapeutics, Inc., Gensight Biologics, AGTC, Prizmatix, Merck KGaA, Elliot Scientific Ltd., Coherent, Inc., The Jackson Laboratory, Scientifica (Judges Scientific Plc Company), Addgene, Shanghai Laser & Optics Century Co., Ltd. (SLOC), Noldus Information Technology, Thorlabs, Inc., and Danaher.
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Optogenetics Actuators & Sensors Market – Market Taxonomy
On the basis of actuators, the global optogenetics actuators & sensors market is segmented into
On the basis of sensors, the global optogenetics actuators & sensors market is segmented into
- Genetically Encoded Calcium Indicators
- Voltage-Sensitive Fluorescent Proteins
- pH Sensors
On the basis of devices, the global optogenetics actuators & sensors market is segmented into
- Light Emitting Diode
On the basis of applications, the optogenetics actuators & sensors market is segmented into
- Retina related disorder
- Neural disorder
- Psychological disorder
On the basis of geography, the optogenetics actuators & sensors market is segmented into:
- North America
- Latin America
- Asia Pacific
- Middle East
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